Gene overlap across human reconstructions

Of the 3,390 genes carried in a human-model GPR (the connected genes behind the Human-genes count), this is how they are shared across the five human reconstructions. Recon4D carries almost all of them; PUFA and Unlumped-FA contribute no genes of their own.

Recon4D
3,281
2,679 unique
IMD
588
102 unique
PUFA
63
0 unique
Unlumped FA
18
0 unique
Drugs
165
6 unique
Union
3,390
distinct genes

Five-set Venn

Numbers are genes in each region. Colours map to reconstructions (legend below).

2679389102864822171512763211
Recon4DIMDPUFAUnlumped FADrugs

Genes shared by N models

1 model
2,787
2 models
500
3 models
84
4 models
19
5 models
0

Region breakdown (15 non-empty)

Intersection#modelsGenes
Recon4D12,679
Recon4D ∩ IMD2389
IMD1102
Recon4D ∩ Drugs286
Recon4D ∩ IMD ∩ Drugs348
Recon4D ∩ PUFA222
Recon4D ∩ IMD ∩ PUFA317
Recon4D ∩ IMD ∩ PUFA ∩ Drugs415
Recon4D ∩ IMD ∩ Unlumped FA312
Recon4D ∩ PUFA ∩ Drugs37
Drugs16
Recon4D ∩ IMD ∩ Unlumped FA ∩ Drugs43
Recon4D ∩ Unlumped FA22
Recon4D ∩ IMD ∩ PUFA ∩ Unlumped FA41
IMD ∩ PUFA21

Snapshot computed 2026-06-20 from human-model GPRs (organismtype Human / Human_drug, excluding legacy Recon3D). The five ellipses are equal-area (a standard 5-set Venn), not proportional to set size. See ADR-091.

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